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¹Department of Radiation Oncology, Muğla Training and Research Hospital, Muğla-Türkiye
²Department of Gynecologic Oncology, Gaziantep City Hospital, Gaziantep-Türkiye
³Department of Medical Oncology, Gaziantep City Hospital, Gaziantep-Türkiye DOI : 10.5505/tjo.2025.4567 Vulvar cancer constitutes around 5% of gynecological cancers within the female genital system. Approximately 90-95% of vulvar cancers are squamous cell carcinoma. This review aims to provide information about the indication, field, technique and doses of radiotherapy in vulvar SCC. Once vulvar cancer is diagnosed, the disease should be staged. Staging can be done according to TNM system or FIGO system. The principal intervention for vulvar squamous cell carcinoma is radical excision, adjuvant radiotherapy and/or chemotherapy may be recommended if there are factors that increase the risk of recurrence as a result of surgical pathology. Radiotherapy for vulvar squamous cell carcinoma will be analyzed in two categories: primary and postoperative radiotherapy. The studies indicate that definitive/neoadjuvant radiotherapy, administered concurrently with chemotherapy in patients with advanced vulvar cancer who are inoperable due to tumor or patient-related factors, demonstrates a high locoregional control rate and acceptable long-term side effects. Postoperative radiotherapy or chemoradiotherapy is recommended for cases with high risk of recurrence. It is recommended to use modern radiotherapy techniques such as IMRT as an radiation modality due to high response rates and low toxicity rates in studies. Radiotherapy and chemoradiotherapy stand out as effective and safe treatment modalities in both definitive and adjuvant treatment of vulvar cancer. Keywords : IMRT; radiotherapy; vulvar cancer