2Akdeniz Üniversitesi Tıp Fakültesi Patoloji AD
3Akdeniz Üniversitesi Tıp Fakültesi İç Hastalıkları Hematoloji Bilim Dalı Primary breast lymphoma is a rare disease and the most frequent subtype is diffuse large cell non-Hodgkin lymphoma. MALT subtype is even more rare and characterized by indolent behavior. It has a more favorable prognosis than the other non-Hodgkin lymphoma subtypes. In this paper, clinic pathologic features and treatment of a primary breast high grade MALT lymphoma case is presented.
A 62 years-old woman presented with a mass in her right breast, which was removed with an excisional biopsy. Tumor was reported as high grade MALT lymphoma after histopathologic examination and immunohistochemical staining. There was not any regional or distant disease outside the breast in clinical and radiological assessment. The patient was diagnosed as Stage IA non-Hodgkin and chemotherapy was planned. She was referred to radiotherapy after the first course, since she could not tolerate chemotherapy. The patient received a total dose of 4680 cGy (180 cGy/fraction) external beam radiation therapy to the whole breast, chest wall, supraclaviculary and axillary lymph nodes. The patient is free of local, regional and distant disease in 52-month follow-up.
Keywords : Primary breast lymphoma, MALT lymphoma, radiotherapy