TURKISH JOURNAL OF ONCOLOGY 2019 , Vol 34 , Num 4
Radiotherapy Technique can be Important on Survival in Patients with Gastric Cancer Treated with Postoperative Chemoradiotherapy
Beyza Şirin ÖZDEMİR1
1Department of Radiation Oncology, Akdeniz university, Antalya-Turkey DOI : 10.5505/tjo.2019.1995 OBJECTIVE
This study aims to investigate the clinical and pathological features of gastric carcinoma and to evaluate the survival of the patients with gastric carcinoma receiving postoperative chemoradiotherapy.

METHODS
In this study, two hundred and four patients who received postoperative chemoradiotherapy for gastric cancer in our clinic from 1999 to 2014 were evaluated retrospectively. Clinical prognostic factors affecting survival were studied.

RESULTS
The median follow-up period was 30.52 months. Overall survival time was 80.47±5.04 months, and the 5-year survival rate was 47.0±4.1%. Overall disease-free survival (DFS) time was 84.58±5.38 months. A lower number of dissected lymph nodes and a higher number of metastatic lymph nodes were found to be related to increased risk of death and also a higher risk for recurrence. Stage 3 cancer was found to have a higher recurrence risk than stage 1 and 2. Recipients of three-dimensional conformal radiotherapy (3DCRT) treatment had a lower risk of death compared to the patients that received 2D treatment.

CONCLUSION
Postoperative chemoradiotherapy should be considered for all the patients with a high risk of recurrence after gastrectomy. In addition to the well-known prognostic factors, such as stage, lymph node metastasis, lymphatic dissection type, radiotherapy technique, was also found to be an important prognostic factor in our study. These results suggest that there is a long-term survival benefit for the patients treated with 3DCRT. Keywords : Chemoradiotherapy; gastric cancer; prognostic factors; radiotherapy; survival